Drug Addiction Treatment
person with hand on chest experiencing the side effects of methadone
By BrightView
Published: March 27, 2025
Updated: April 24, 2025

Methadone is a long-acting synthetic opioid commonly used in medication assisted treatment programs to help people overcome opioid dependence. A methadone treatment program, as part of a comprehensive treatment plan, can alleviate withdrawal symptoms and reduce cravings, facilitating a smoother transition to recovery.

However, it’s essential to understand the potential side effects and impacts of methadone to make informed decisions about its use. 

What to Expect When Taking Methadone 

Initiating a methadone treatment program involves regular dosing, typically administered daily under medical supervision. The medication works by binding to the same receptors in the brain as other opioids, but without producing the intense euphoria, thereby helping to stabilize the patient’s condition and reduce withdrawal symptoms. Patients may experience certain side effects as their bodies adjust to the medication. 

Common Side Effects of Methadone 

Methadone, like other medications, can cause side effects. Common side effects include: 

  • Digestive issues – Nausea, vomiting, constipation, or stomach pain are frequently reported. 
  • Drowsiness – Feelings of sleepiness or sedation can occur, especially during the initial stages of treatment. 
  • Headaches – Some individuals may experience headaches as their bodies adapt to methadone. 
  • Dizziness or lightheadedness – These sensations can happen, particularly when standing up quickly. 
  • Dry mouth – Some people notice a decrease in saliva production, leading to a dry sensation in the mouth. 

These side effects are typically mild and may diminish as treatment continues. Communicating any persistent or severe symptoms to a healthcare provider is crucial. 

Serious Side Effects and Risks 

While methadone is effective in treating opioid dependence, it carries risks of more severe side effects, including: 

  • Respiratory depression – Methadone can slow breathing, which may be life-threatening if not monitored properly. 
  • Cardiac issues – There is a potential for heart-related problems, such as arrhythmias. 
  • Severe allergic reactions – Symptoms like swelling of the face, lips, tongue, or throat require immediate medical attention. 

Patients should seek immediate medical help if they experience shallow breathing, chest pain, lightheadedness, confusion, or severe drowsiness. 

Physical Effects of Taking Methadone 

Beyond the common side effects, methadone can have other physical effects: 

  • Weight changes – Some people may experience weight gain or loss during treatment. 
  • Sexual dysfunction – Decreased libido or difficulties with sexual performance have been reported. 
  • Sweating – Increased perspiration is a noted side effect for some patients. 

Regular consultations with healthcare providers are essential to monitor these effects and adjust treatment as necessary. 

Does Methadone Impact Mental Health? 

Methadone’s effects on mental well-being can vary: 

  • Mood changes – Some patients report feelings of anxiety, depression, or irritability. 
  • Cognitive effects – There may be instances of confusion or difficulty concentrating. 

It’s important to note that untreated opioid dependence often has a more detrimental impact on mental health than the potential side effects of methadone. Understanding the potential side effects of methadone helps patients and their families feel more informed and empowered during treatment. Engaging in counseling and support services alongside methadone treatment can enhance mental well-being. 

Can You Live a Normal Life on Methadone? 

Yes, many patients on methadone maintenance therapy lead fulfilling lives. Methadone helps stabilize patients, allowing them to engage in daily activities, maintain employment, and nurture personal relationships. Adherence to the prescribed treatment plan and participation in supportive therapies are crucial for achieving a balanced lifestyle. Once stabilized on methadone, many patients safely work and drive, but it is important to follow your medical provider’s guidance.  

Call Today to Find Methadone Treatment at BrightView 

At BrightView, we offer comprehensive outpatient treatment programs that integrate medication assisted treatment, including methadone, with individual and group counseling. Our approach focuses on providing immediate access to care, a supportive environment, and personalized treatment plans.  

If you or a loved one is struggling with opioid dependence, contact BrightView at 888.501.9865 or schedule online. We’re on standby to help you learn more about our methadone treatment programs and how we can support your journey to recovery.